Nanomaterials possess unique properties which allows them to be used as labels in various kinds of immunoassays and biosensors. In our lab we develop nanoparticles-based reagents for bioassays. We synthesize polymer-coated inorganic nanopaticles (magnetic, catalytic or brigtly colored) or polymer nanoparticles loaded with reporter luminescent or catalytic complexes. Conjugates of prepared nanoparticles with monoclonal antibodies, aptamers, and other recognition molecules we utilize to develop quantitative assays in homogeneous, dot blot or ELISA-like format.